![]() ![]() ![]() These are most prominent in the anterior cervical, inguinal and axillary regions and continue to increase in size until the age of 8-12, after which atrophy occurs. Most children have palpable lymph nodes, the relative size of which could qualify for lymphadenopathy in an adult. Presenting symptoms of more indolent diseases (eg, tuberculosis, malignancy) may occur some time after the development of the initial lymphadenopathy.Ī sexual history and history of intravenous drug use should also be elicited. īearing in mind the extensive list of differential diagnoses, it is important to keep the patient under review if spontaneous recovery does not occur. ![]() Supraclavicular and infraclavicular lymph nodes are always suspicious of an underlying malignancy, particularly in those aged over 40 years. Persistent fever, night sweats, general malaise or weight loss may be pointers to significant disease. General lymphadenopathy symptoms (presentation) HistoryĪ history should include the duration of the lymphadenopathy, whether any other household members are acutely ill and whether there are any accompanying symptoms. 4% of patients aged 40 years or older who present with unexplained lymphadenopathy are found to have an underlying cancer, but for those younger than 40 years this falls to 0.4%. In primary care unexplained lymphadenopathy has an annual incidence of 0.6%.įewer than 1 in 100 of these cases have a malignant aetiology, but this increases as the age of the patient increases. ![]()
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